CD8a (Cytotoxic- & Suppressor T-Cell Marker) [clone C8/468+144B], anti-human

Description: CD8 molecule consists of two chains, termed α and β chain, which are expressed as a disulphide-linked α/β heterdimer or as an α/α homodimer on T cell subset, thymocytes and NK cells. The majority of CD8+ T cells express CD8 as α/β heterdimer. CD8 functions as a coreceptor in concert with TCR for binding the MHC class I/peptide complex. The HIV-2 envelope glycoprotein binds CD8α chain (but not β chain)Localization: membraneDilution: 50-200Positive Control: tonsilHIER: citrate pH6.0Status: RUO