CD8a polyclonal, anti-human

Quantity: 100 µg

Background:
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. It is mapped to 2p11.2. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene also encodes the CD8 alpha chain isoforms.

Description:
Rabbit IgG polyclonal antibody for T-cell surface glycoprotein CD8 alpha chain (CD8A) detection. Tested with WB, IHC-P in Human.

Synonyms:
alpha polypeptide (p32) antibody, CD 8a antibody, CD8 alpha chain antibody, CD8 antibody, CD8 antigen alpha chain antibody, CD8 antigen alpha polypeptide antibody, CD8 antigen alpha polypeptide (p32) antibody, CD8a antibody, CD8a antigen antibody, CD8a molecule antibody, CD8A_HUMAN antibody, Leu 2 antibody, Leu2 antibody, Leu2 T lymphocyte antigen antibody, Ly3 antibody, LYT3 antibody, MAL antibody, OKT8 T cell antigen antibody, OTTHUMP00000160760 antibody, OTTHUMP00000160764 antibody, OTTHUMP00000203528 antibody, OTTHUMP00000203721 antibody, p32 antibody, T cell antigen Leu2 antibody, T cell co receptor antibody, T cell coreceptor antibody, T cell surface glycoprotein CD8 alpha chain antibody, T lymphocyte differentiation antigen T8/Leu 2 antibody, T lymphocyte differentiation antigen T8/Leu2 antibody, T-cell surface glycoprotein CD8 alpha chain antibody, T-lymphocyte differentiation antigen T8/Leu-2 antibody, T8 T cell antigen antibody, T8/Leu-2 T-lymphocyte differentiation antigen antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human CD8 alpha recombinant protein (Position: S22-A187). Human CD8 alpha shares 49% and 47% amino acid (aa) sequence identity with mouse and rat CD8 alpha, respectively.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.