CD8A polyclonal, anti-human
€295.00
In stock
SKU
K007994P
Catalog Number: K007994P
Size: 100 μl
Other size: 50 μl
Isotype: Rabbit IgG
Applications: WB, IHC
Request Manual
Questions? Contact us!
Size: 100 μl
Other size: 50 μl
Isotype: Rabbit IgG
Applications: WB, IHC
Request Manual
Questions? Contact us!
Background:
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms: CD8, MAL, p32, Leu2
Cellular Location: Membrane
Immunogen:
A synthetic peptide of human CD8A
Gene Symbol: CD8A
Gene ID: 925
Swiss prot: P01732
Calculated MW: 26kDa
Recommended dilution:
WB 1:200-1000, IHC 1:30-150,
Purity:
Affinity purification
Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
Storage:
Store at -20℃. Avoid freeze / thaw cycles.
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms: CD8, MAL, p32, Leu2
Cellular Location: Membrane
Immunogen:
A synthetic peptide of human CD8A
Gene Symbol: CD8A
Gene ID: 925
Swiss prot: P01732
Calculated MW: 26kDa
Recommended dilution:
WB 1:200-1000, IHC 1:30-150,
Purity:
Affinity purification
Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
Storage:
Store at -20℃. Avoid freeze / thaw cycles.
| Is Featured? | No |
|---|
Write Your Own Review