CD8B polyclonal, anti-human, mouse, rat

Background:
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified.

Synonyms: CD8B1, LEU2, LY3, LYT3, P37

Cellular Location: Cell membrane Secreted Single-pass type I membrane protein Single-pass type I membrane protein

Immunogen:
Recombinant protein of human CD8B

Gene Symbol: CD8B

Gene ID: 926

Swiss prot: P10966

Calculated MW: 24kDa

Recommended dilution:
WB 1:200-500

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.