CD155 polyclonal, anti-human, mouse, rat
€470.00
In stock
SKU
AC-AP73811
Background:
Mediates NK cell adhesion and triggers NK cell effector functions. Binds two different NK cell receptors: CD96 and CD226. These interactions accumulates at the cell-cell contact site, leading to the formation of a mature immunological synapse between NK cell and target cell. This may trigger adhesion and secretion of lytic granules and IFN-gamma and activate cytoxicity of activated NK cells. May also promote NK cell-target cell modular exchange, and PVR transfer to the NK cell. This transfer is more important in some tumor cells expressing a lot of PVR, and may trigger fratricide NK cell activation, providing tumors with a mechanism of immunoevasion. Plays a role in mediating tumor cell invasion and migration.
Other Names:
PVR; PVS; Poliovirus receptor; Nectin-like protein 5; NECL-5; CD155
Antigen Type: synthetic peptide
Antigen Type: PVR
Gene ID: 5817
Primary Accession: P15151
Mediates NK cell adhesion and triggers NK cell effector functions. Binds two different NK cell receptors: CD96 and CD226. These interactions accumulates at the cell-cell contact site, leading to the formation of a mature immunological synapse between NK cell and target cell. This may trigger adhesion and secretion of lytic granules and IFN-gamma and activate cytoxicity of activated NK cells. May also promote NK cell-target cell modular exchange, and PVR transfer to the NK cell. This transfer is more important in some tumor cells expressing a lot of PVR, and may trigger fratricide NK cell activation, providing tumors with a mechanism of immunoevasion. Plays a role in mediating tumor cell invasion and migration.
Other Names:
PVR; PVS; Poliovirus receptor; Nectin-like protein 5; NECL-5; CD155
Antigen Type: synthetic peptide
Antigen Type: PVR
Gene ID: 5817
Primary Accession: P15151
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