CD97 Antibody (C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP13768b
Background:
This gene is a member of the EGF-TM7 family of class IIseven-span transmembrane (7-TM) molecules, likely encoded by a genecluster on the short arm of chromosome 19. The encoded product is aglycoprotein that is present on the surface of most activatedleukocytes and spans the membrane seven times, which is a definingfeature of G protein-coupled receptors. The protein has an extendedextracellular region with several N-terminal epidermal growthfactor (EGF)-like domains, which mediate binding to its cellularligand, decay accelerating factor (DAF, CD55), a regulatory proteinof the complement cascade. The presence of structural featurescharacteristic of extracellular matrix proteins and transmembraneproteins suggests that this protein is a receptor involved in bothcell adhesion and signaling processes early after leukocyteactivation. Alternative splicing has been observed for this geneand three variants have been found.
Other Names:
CD97 antigen, Leukocyte antigen CD97, CD97, CD97 antigen subunit alpha, CD97 antigen subunit beta, CD97
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13768b was selected from the C-term region of CD97. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: ADGRE5 (HGNC:1711)
Gene ID: 976
Primary Accession: P48960
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene is a member of the EGF-TM7 family of class IIseven-span transmembrane (7-TM) molecules, likely encoded by a genecluster on the short arm of chromosome 19. The encoded product is aglycoprotein that is present on the surface of most activatedleukocytes and spans the membrane seven times, which is a definingfeature of G protein-coupled receptors. The protein has an extendedextracellular region with several N-terminal epidermal growthfactor (EGF)-like domains, which mediate binding to its cellularligand, decay accelerating factor (DAF, CD55), a regulatory proteinof the complement cascade. The presence of structural featurescharacteristic of extracellular matrix proteins and transmembraneproteins suggests that this protein is a receptor involved in bothcell adhesion and signaling processes early after leukocyteactivation. Alternative splicing has been observed for this geneand three variants have been found.
Other Names:
CD97 antigen, Leukocyte antigen CD97, CD97, CD97 antigen subunit alpha, CD97 antigen subunit beta, CD97
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13768b was selected from the C-term region of CD97. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: ADGRE5 (HGNC:1711)
Gene ID: 976
Primary Accession: P48960
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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