CD97 antibody (clone 5D5), anti-human
€435.00
In stock
SKU
AC-AT1451a
Catalog Number: AC-AT1451a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, E
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, E
Request Information AC-AT1451a">Request Information
Background:
This gene is a member of the EGF-TM7 family of class II seven-span transmembrane (7-TM) molecules, likely encoded by a gene cluster on the short arm of chromosome 19. The encoded product is a glycoprotein that is present on the surface of most activated leukocytes and spans the membrane seven times, which is a defining feature of G protein-coupled receptors. The protein has an extended extracellular region with several N-terminal epidermal growth factor (EGF)-like domains, which mediate binding to its cellular ligand, decay accelerating factor (DAF, CD55), a regulatory protein of the complement cascade. The presence of structural features characteristic of extracellular matrix proteins and transmembrane proteins suggests that this protein is a receptor involved in both cell adhesion and signaling processes early after leukocyte activation. Alternative splicing has been observed for this gene and three variants have been found.
Other Names:
CD97 antigen, Leukocyte antigen CD97, CD97, CD97 antigen subunit alpha, CD97 antigen subunit beta, CD97
Antigen Type:
Recombinant Protein
Gene Name: ADGRE5 (HGNC:1711)
Gene ID: 976
NCBI Accession: NP_001020331.1;NP_001775.2;NP_510966.1
Primary Accession: P48960
Other Accession: NM_078481
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene is a member of the EGF-TM7 family of class II seven-span transmembrane (7-TM) molecules, likely encoded by a gene cluster on the short arm of chromosome 19. The encoded product is a glycoprotein that is present on the surface of most activated leukocytes and spans the membrane seven times, which is a defining feature of G protein-coupled receptors. The protein has an extended extracellular region with several N-terminal epidermal growth factor (EGF)-like domains, which mediate binding to its cellular ligand, decay accelerating factor (DAF, CD55), a regulatory protein of the complement cascade. The presence of structural features characteristic of extracellular matrix proteins and transmembrane proteins suggests that this protein is a receptor involved in both cell adhesion and signaling processes early after leukocyte activation. Alternative splicing has been observed for this gene and three variants have been found.
Other Names:
CD97 antigen, Leukocyte antigen CD97, CD97, CD97 antigen subunit alpha, CD97 antigen subunit beta, CD97
Antigen Type:
Recombinant Protein
Gene Name: ADGRE5 (HGNC:1711)
Gene ID: 976
NCBI Accession: NP_001020331.1;NP_001775.2;NP_510966.1
Primary Accession: P48960
Other Accession: NM_078481
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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