CD99/CD99 (mic-2) Antibody (C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP14143b
Background:
The protein encoded by this gene is a cell surfaceglycoprotein involved in leukocyte migration, T-cell adhesion,ganglioside GM1 and transmembrane protein transport, and T-celldeath by a caspase-independent pathway. In addition, the encodedprotein may have the ability to rearrange the actin cytoskeletonand may also act as an oncosuppressor in osteosarcoma. CyclophilinA binds to CD99 and may act as a signaling regulator of CD99. Thisgene is found in the pseudoautosomal region of chromosomes X and Yand escapes X-chromosome inactivation. Two transcript variantsencoding different isoforms have been found for this gene.
Other Names:
CD99 antigen, E2 antigen, Protein MIC2, T-cell surface glycoprotein E2, CD99, CD99, MIC2, MIC2X, MIC2Y
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP14143b was selected from the C-term region of CD99/CD99. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: CD99
Gene ID: 4267
Primary Accession: P14209
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The protein encoded by this gene is a cell surfaceglycoprotein involved in leukocyte migration, T-cell adhesion,ganglioside GM1 and transmembrane protein transport, and T-celldeath by a caspase-independent pathway. In addition, the encodedprotein may have the ability to rearrange the actin cytoskeletonand may also act as an oncosuppressor in osteosarcoma. CyclophilinA binds to CD99 and may act as a signaling regulator of CD99. Thisgene is found in the pseudoautosomal region of chromosomes X and Yand escapes X-chromosome inactivation. Two transcript variantsencoding different isoforms have been found for this gene.
Other Names:
CD99 antigen, E2 antigen, Protein MIC2, T-cell surface glycoprotein E2, CD99, CD99, MIC2, MIC2X, MIC2Y
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP14143b was selected from the C-term region of CD99/CD99. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: CD99
Gene ID: 4267
Primary Accession: P14209
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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