CD99R (clone HIT4), anti-human

Protein Family: CAM Ligands, Cell Adhesion Molecules, Cellular Antigens

Pathway and Disease: Immune System, Signaling Molecules and Interaction

Description:
The CD99R (HIT4) antibody recognizes a 32-kDa type-I single chain highly glycosylated transmembrane protein. CD99R is an isoform of CD99 with restricted cell distribution. CD99R antigen is expressed on hematopoietic progenitors, thymocytes, a subset of T cells (30-42% of CD4+ cells and 15-23% of CD8+ cells), NK cells and some leukemic cells, but is not on B cells, erythrocytes and platelets. In leukemia, the co-expression of CD99R antigen and CD38 antigen predicts that the leukemic cells are in early or immature stage.

Alternate Names: CD99, CD99 antigen, T-cell surface glycoprotein E2, E2 antigen, Protein MIC2, 12E7, CD99 Restricted, CD99R

Application Notes: Purified antibody is suitable for immunohistochemistry with acetone-fixed frozen sections. E: 1:500-1:1,000; FC: 1:200-1:1,000; IHC: 1:200-1:500

Accession No.: P14209

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

Product Citations:
Shen DC., et al. 1986. Chinese J. of Immunology. 2(6): 331
Chen Z., et al. 1987. Shanghai J. of Immunology. 7(1): 1
Yang CY., et al. 1994. Chinese J. of Microbiology and Immunology. 14(2): 104
Yang CY., et al. 1995. Shanghai J. of Immunology. 15(1): 4
Schlossman S. et al., eds. 1995. Leucocyte Typing V: White Cell Differentiation Antigens. P246, Oxford University Press, New York.