CDA Antibody (C-term) Blocking Peptide

Background:
CDA forms a homotetramer that catalyzes the irreversible hydrolytic deamination of cytidine and deoxycytidine to uridine and deoxyuridine, respectively. This protein is one of several deaminases responsible for maintaining the cellular pyrimidine pool. Mutations in the CDA gene are associated with decreased sensitivity to the cytosine nucleoside analogue cytosine arabinoside used in the treatment of certain childhood leukemias.

Other Names:
Cytidine deaminase, Cytidine aminohydrolase, CDA, CDD

Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP2868b was selected from the C-term region of human CDA. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

Gene Name: CDA (HGNC:1712)

Gene ID: 978
Primary Accession: P32320
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.