Cdc14 polyclonal, anti-human, mouse
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In stock
SKU
AC-AP8440a
Catalog Number: AC-AP8440a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB7269
Applications: FC, IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB7269
Applications: FC, IHC-P, WB
Datasheet
Request Information
Background:
The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms.
Other Names:
Dual specificity protein phosphatase CDC14A, CDC14 cell division cycle 14 homolog A, CDC14A
Target/Specificity:
This Cdc14 antibody is generated from rabbits immunized with a recombinant protein encoding aa 1~379 of human cdc14.
Antigen Type: Recombinant Protein
Gene Name: CDC14A
Gene ID: 8556
Primary Accession: Q9UNH5
NCBI Accession: NP_003663.2;NP_201569.1;NP_201570.1
Other Accession: NP_003663
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by dialysis against PBS.
The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms.
Other Names:
Dual specificity protein phosphatase CDC14A, CDC14 cell division cycle 14 homolog A, CDC14A
Target/Specificity:
This Cdc14 antibody is generated from rabbits immunized with a recombinant protein encoding aa 1~379 of human cdc14.
Antigen Type: Recombinant Protein
Gene Name: CDC14A
Gene ID: 8556
Primary Accession: Q9UNH5
NCBI Accession: NP_003663.2;NP_201569.1;NP_201570.1
Other Accession: NP_003663
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by dialysis against PBS.
| Is Featured? | No |
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