CDC14B polyclonal (Center), anti-human
€0.00
In stock
SKU
AC-AP9081c
Catalog Number: AC-AP9081c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB16909
Applications: FC, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB16909
Applications: FC, WB
Datasheet
Request Information
Background:
CDC14B is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms.
Other Names:
Dual specificity protein phosphatase CDC14B, CDC14 cell division cycle 14 homolog B, CDC14B
Target/Specificity:
This CDC14B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 188-215 amino acids from the Central region of human CDC14B.
Antigen Region:
188-215
Antigen Type: Synthetic Peptide
Gene Name: CDC14B
Gene ID: 8555
Primary Accession: O60729
NCBI Accession: NP_001070649.1;NP_003662.1;NP_201588.1
Other Accession: A4D256; Q6PFY9
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
CDC14B is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms.
Other Names:
Dual specificity protein phosphatase CDC14B, CDC14 cell division cycle 14 homolog B, CDC14B
Target/Specificity:
This CDC14B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 188-215 amino acids from the Central region of human CDC14B.
Antigen Region:
188-215
Antigen Type: Synthetic Peptide
Gene Name: CDC14B
Gene ID: 8555
Primary Accession: O60729
NCBI Accession: NP_001070649.1;NP_003662.1;NP_201588.1
Other Accession: A4D256; Q6PFY9
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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