CDC16 polyclonal, anti-human, mouse, rat

Background:
The protein encoded by this gene functions as a protein ubiquitin ligase and is a component of the multiprotein APC complex. The APC complex is a cyclin degradation system that governs exit from mitosis by targeting cell cycle proteins for degredation by the 26S proteasome. Each component protein of the APC complex is highly conserved among eukaryotic organisms. This protein, and other APC complex proteins, contain a tetratricopeptide repeat (TPR) domain; a protein domain that is often involved in protein-protein interactions and the assembly of multiprotein complexes. Multiple alternatively spliced transcript variants, encoding distinct proteins, have been identified.

Synonyms: ANAPC6, APC6, CDC16Hs, CUT9

Cellular Location: Cytoplasm centrosome cytoskeleton microtubule organizing center spindle

Immunogen:
Recombinant protein of human CDC16

Gene Symbol: CDC16

Gene ID: 8881

Swiss prot: Q13042

Calculated MW: 72kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200, IF 1:50-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.