CDC25A Polyclonal Antibody

Background:
CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene.

Research Area: Cancer, Cell Biology, Epigenetics and Nuclear Signaling

Synonyms:
Cdc 25a, CDC25A, CDC25A2, CDC25A2 CAG isoform, Cell division cycle 25 homolog A (S. pombe), Cell division cycle 25A, Cell division cycle 25A isoform a, Cell division cycle 25A isoform b, D9Ertd393e, Dual specificity phosphatase Cdc25A, M phase inducer phosphatase 1, M-phase inducer phosphatase 1, MGC115549, MPIP1

Immunogen: Synthetic peptide of human CDC25A

Swissprot: P30304
Gene Accession: NP_001780

Calculated MW: 59 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.2 mg/mL
Dilution: WB 1:200-1:1000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-6947/sc-97/sc-7157