CDC25B polyclonal, anti-human

Background:
CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist. 

Synonyms: CDC25B, CDC25HU2, M phase inducer phosphatase 2

Cellular Location: Cytoplasm 

Immunogen:
Recombinant protein of human CDC25B

Gene Symbol: CDC25B

Gene ID: 994

Swiss prot: P30305

Calculated MW: 65kDa

Recommended dilution:
IHC 1:50-200

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.