Cdc25C (clone ), anti-human
€388.00
In stock
SKU
MB0124
Background:
Cyclin dependent kinases are positively regulated by association with cyclins and negatively regulated by binding to inhibitory subunits. The activity of cyclin dependent kinases is also regulated by the phosphorylation status, which is controlled by the antagonistic action of Wee1 kinase and CDC25 phosphatases. Three CDC25 genes are present in human cells: CDC25A, CDC25B, and CDC25C. These three genes function at different phases of the cell cycle. Whereas CDC25A and CDC25B are expressed throughout the cell cycle, with peak expression in G1 for CDC25A and in both G1 S phase and G2 for CDC25B, CDC25C is predominantly expressed in G2.
Alternative Name:
M-phase inducer phosphatase 3, Dual specificity phosphatase Cdc25C, CDC25C
Application Dilution: WB: 1:500~1:1000
Specificity: Cdc25C mAb detects endogenous levels of Cdc25C protein.
Immunogen:
Recombinant full length Human Cdc25C.
MW: Predicted band size: 60/75KDa, Observed band size: 75KDa
Swis Prot.: P30307
Purification & Purity:
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
Ascitic fluid containing 0.03% sodium azide.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Cyclin dependent kinases are positively regulated by association with cyclins and negatively regulated by binding to inhibitory subunits. The activity of cyclin dependent kinases is also regulated by the phosphorylation status, which is controlled by the antagonistic action of Wee1 kinase and CDC25 phosphatases. Three CDC25 genes are present in human cells: CDC25A, CDC25B, and CDC25C. These three genes function at different phases of the cell cycle. Whereas CDC25A and CDC25B are expressed throughout the cell cycle, with peak expression in G1 for CDC25A and in both G1 S phase and G2 for CDC25B, CDC25C is predominantly expressed in G2.
Alternative Name:
M-phase inducer phosphatase 3, Dual specificity phosphatase Cdc25C, CDC25C
Application Dilution: WB: 1:500~1:1000
Specificity: Cdc25C mAb detects endogenous levels of Cdc25C protein.
Immunogen:
Recombinant full length Human Cdc25C.
MW: Predicted band size: 60/75KDa, Observed band size: 75KDa
Swis Prot.: P30307
Purification & Purity:
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
Ascitic fluid containing 0.03% sodium azide.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
| Is Featured? | No |
|---|
Write Your Own Review