CDC27 Polyclonal Antibody

Background:
The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.

Research Area: Cancer, Cell biology

Synonyms:
ANAPC3, Anaphase Promoting Complex 3, Anaphase promoting complex protein 3, Anaphase Promoting Complex Subunit 3, Anaphase-promoting complex subunit 3, APC 3, APC3, Cdc 27, Cdc27, CDC27 homolog, CDC27, CDC27Hs, Cell Division Cycle 27, Cell division cycle protein 27 homolog, D0S1430E, D17S978E, H NUC, H-NUC, HNUC, Nuc2 homolog

Immunogen: Synthetic peptide of human CDC27

Swissprot: P30260
Gene Accession: NP_001107563

Calculated MW: 92 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.3 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:25-1:100

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-6391/sc-6392/sc-5618