CDC42 polyclonal, anti-human, mouse, rat
€484.00
In stock
SKU
254045
Protein Family: Enzymes
Pathway and Disease: Signaling Molecules and Interaction
Description:
CDC42 is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to S. cerevisiae CDC42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. CDC42 is thought to regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. At least two isoforms of CDC42 are known to exist.
Alternate Names: CDC42, Cell division cycle 42, G25K
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500
Accession No.: NP_001782
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within human CDC42.
Format: Each vial contains 0.1 ml IgY in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Signaling Molecules and Interaction
Description:
CDC42 is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to S. cerevisiae CDC42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. CDC42 is thought to regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. At least two isoforms of CDC42 are known to exist.
Alternate Names: CDC42, Cell division cycle 42, G25K
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500
Accession No.: NP_001782
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within human CDC42.
Format: Each vial contains 0.1 ml IgY in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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