CDC42BPA polyclonal, anti-human, mouse, rat

Background:
The protein encoded by this gene is a member of the Serine/Threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described, and the full-length nature of two of them has been reported.

Synonyms: MRCK, MRCKA, PK428

Cellular Location: Cytoplasm

Immunogen:
A synthetic peptide of human CDC42BPA

Gene Symbol: CDC42BPA

Gene ID: 8476

Swiss prot: Q5VT25

Calculated MW: 197 kDa

Recommended dilution:
WB 1:500-2000, IHC 1:30-150,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.