CDC42BPA Polyclonal Antibody

Background:
The protein encoded by this gene is a member of the Serine/Threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described, and the full-length nature of two of them has been reported.

Research Area: Cancer, Signal Transduction

Synonyms:
A930014J19Rik, CDC42 binding protein kinase alpha (DMPK like), CDC42 binding protein kinase alpha, CDC42 binding protein kinase alpha dmpk like, CDC42 binding protein kinase beta, CDC42-binding protein kinase alpha, CDC42BPA, DKFZp686L1738, DKFZp686P1738, DMPK like, DMPK-like alpha, FLJ23347, KIAA0451, MGC189823, MRCK alpha, mrck, mrcka, MRCKA, Myotonic dystrophy kinase related CDC42 binding protein kinase alpha, Myotonic dystrophy kinase-related CDC42-binding kinase alpha, Myotonic dystrophy protein kinase-like alpha, OTTHUMP00000035727, OTTHUMP00000035728, OTTHUMP00000035729, OTTHUMP00000035730, pk428, RP5-1087E8.4, Ser thr protein kinase PK428, Ser thr protein kinase related to the myotonic dystrophy protein kinase, Serine/threonine protein kinase MRCK alpha, Serine/threonine-protein kinase MRCK alpha

Immunogen: Synthetic peptide of human CDC42BPA

Swissprot: Q5VT25
Gene Accession: XP005273381

Calculated MW: 197 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.