CDC42EP1 polyclonal, anti-human

Background:
MSE55 also known as Borg5 or binder of Rho GTPases 5 is a Cdc42 effector protein that induces long cellular extensions in fibroblasts. MSE55 also increases and mediates actin cytoskeleton reorganization at the plasma membrane. MSE55 is a nonkinase CRIB (Cdc42/Rac interactive-binding) domain-containing molecule. An intact CRIB domain is required for the GTP-dependent binding of MSE55 to Cdc42. MSE55 is expressed in a tissue-specific manner in endothelial and bone marrow stromal cells. MSE55 may have a functional role in hematopoiesis or as a negative regulator of Rho GTPase signaling.

Alternative Name:
CDC42EP1, 55 kDa bone marrow stromal/endothelial cell protein, Binder of Rho GTPases 5, Bone marrow stromal/endothelial cell protein, 55-KD, BORG 5, BORG5, BORG5, CDC42 effector protein (Rho GTPase binding) 1, Cdc42 effector protein 1, Cdc42ep1, CEP 1, CEP1, MGC15316, MSE 55, MSE55, OTTHUMP00000028709, Serum constituent protein, Serum protein MSE55,

Application Dilution:
WB:1:1,000-1:2,000

Specificity: CDC42EP1 polyclonal antibody detects endogenous levels of CDC42EP1 protein.

Immunogen:
recombinant protein

MW: 60 kDa

Swiss-Prot: Q00587(Human)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.