CDC42EP2 antibody (clone 2H7), anti-human
€435.00
In stock
SKU
AC-AT1466a
Catalog Number: AC-AT1466a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB
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Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB
Request Information AC-AT1466a">Request Information
Background:
CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. Coexpression of this protein with dominant negative mutant CDC42 protein in fibroblast was found to induce pseudopodia formation, which suggested a role of this protein in actin filament assembly and cell shape control.
Other Names:
Cdc42 effector protein 2, Binder of Rho GTPases 1, CDC42EP2, BORG1, CEP2
Antigen Type:
Recombinant Protein
Gene Name: CDC42EP2
Gene ID: 10435
NCBI Accession: NP_006770.1
Primary Accession: O14613
Other Accession: NM_006779
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. Coexpression of this protein with dominant negative mutant CDC42 protein in fibroblast was found to induce pseudopodia formation, which suggested a role of this protein in actin filament assembly and cell shape control.
Other Names:
Cdc42 effector protein 2, Binder of Rho GTPases 1, CDC42EP2, BORG1, CEP2
Antigen Type:
Recombinant Protein
Gene Name: CDC42EP2
Gene ID: 10435
NCBI Accession: NP_006770.1
Primary Accession: O14613
Other Accession: NM_006779
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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