cdc45 polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS7415
Background:
The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010]
Alternative Name:
CDC 45, CDC 45L, CDC45 (cell division cycle 45, S.cerevisiae homolog) like, CDC45, CDC45 cell division cycle 45 like, CDC45 like, CDC45 related protein, CDC45_HUMAN, CDC45L2, Cell division control protein 45 homolog, Cell division cycle 45 like 2, Cell division cycle 45 like, PORC PI 1, PORC-PI-1,
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: cdc45 polyclonal antibody detects endogenous levels of cdc45 protein.
Immunogen:
Recombinant full length Human cdc45.
MW: ~64 kDa
Swis Prot.: O75419
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010]
Alternative Name:
CDC 45, CDC 45L, CDC45 (cell division cycle 45, S.cerevisiae homolog) like, CDC45, CDC45 cell division cycle 45 like, CDC45 like, CDC45 related protein, CDC45_HUMAN, CDC45L2, Cell division control protein 45 homolog, Cell division cycle 45 like 2, Cell division cycle 45 like, PORC PI 1, PORC-PI-1,
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: cdc45 polyclonal antibody detects endogenous levels of cdc45 protein.
Immunogen:
Recombinant full length Human cdc45.
MW: ~64 kDa
Swis Prot.: O75419
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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