CDC45L antibody (clone 3F11-1F3), anti-human
€435.00
In stock
SKU
AC-AT1467a
Catalog Number: AC-AT1467a
Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: WB, IF, E
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Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: WB, IF, E
Request Information AC-AT1467a">Request Information
Background:
The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Other Names:
Cell division control protein 45 homolog, PORC-PI-1, CDC45, CDC45L, CDC45L2
Antigen Type:
Recombinant Protein
Gene Name: CDC45 (HGNC:1739)
Gene ID: 8318
NCBI Accession: NP_001171481.1;NP_001171482.1;NP_003495.1
Primary Accession: O75419
Other Accession: BC006232
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Other Names:
Cell division control protein 45 homolog, PORC-PI-1, CDC45, CDC45L, CDC45L2
Antigen Type:
Recombinant Protein
Gene Name: CDC45 (HGNC:1739)
Gene ID: 8318
NCBI Accession: NP_001171481.1;NP_001171482.1;NP_003495.1
Primary Accession: O75419
Other Accession: BC006232
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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