CDC45L polyclonal (Center), anti-human
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In stock
SKU
AC-AP9881c
Catalog Number: AC-AP9881c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB23958
Applications: FC, IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB23958
Applications: FC, IHC-P, WB
Datasheet
Request Information
Background:
The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Multiple polyadenlyation sites of this gene are reported.
Other Names:
Cell division control protein 45 homolog, PORC-PI-1, CDC45, CDC45L, CDC45L2
Target/Specificity:
This CDC45L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 236-263 amino acids from the Central region of human CDC45L.
Antigen Region:
236-263
Antigen Type: Synthetic Peptide
Gene Name: CDC45 (HGNC:1739)
Gene ID: 8318
Primary Accession: O75419
NCBI Accession: NP_001171481.1;NP_001171482.1;NP_003495.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Multiple polyadenlyation sites of this gene are reported.
Other Names:
Cell division control protein 45 homolog, PORC-PI-1, CDC45, CDC45L, CDC45L2
Target/Specificity:
This CDC45L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 236-263 amino acids from the Central region of human CDC45L.
Antigen Region:
236-263
Antigen Type: Synthetic Peptide
Gene Name: CDC45 (HGNC:1739)
Gene ID: 8318
Primary Accession: O75419
NCBI Accession: NP_001171481.1;NP_001171482.1;NP_003495.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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