Cdc6 polyclonal, anti-human, rat

Quantity: 100 µg

Background:
Cell division control ptotein 6 homolog, also called CDC18L or CDC6, is a protein that in humans is encoded by the CDC6 gene. By analysis of somatic cell hybrids and by fluorescence in situ hybridization, this gene is mapped to 17q21.2. The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. And this protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins. This gene is involved in the initiation of DNA replication.

Description:
Rabbit IgG polyclonal antibody for Cell division control protein 6 homolog (CDC6) detection. Tested with WB, IHC-P in Human, Rat.

Synonyms:
Cdc 18L antibody, Cdc 6 antibody, CDC18 (cell division cycle 18, S.pombe, homolog) like antibody, CDC18 (S.pombe) antibody, Cdc18 related protein antibody, CDC18(S.pombe) antibody, Cdc18-related protein antibody, Cdc18L antibody, cdc6 antibody, CDC6 cell division cycle 6 homolog antibody, CDC6 related protein antibody, CDC6-related protein antibody, CDC6_HUMAN antibody, Cdc6p antibody, Cell Cycle Controller antibody, CELL CYCLE CONTROLLER CDC6 antibody, Cell division control protein 6 antibody, Cell division control protein 6 homolog antibody, Cell Division Cycle 18 antibody, Cell division cycle 6 homolog (S. cerevisiae) antibody, Cell division cycle 6 homolog antibody, HsCDC 6 antibody, HsCDC18 antibody, HsCDC6 antibody, p62 antibody, p62(cdc 6) antibody, p62(cdc6) antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human Cdc6 recombinant protein (Position: V147-A549). Human Cdc6 shares 87.3% amino acid (aa) sequence identity with mouse Cdc6.E.coli-derived human Cdc6 recombinant protein (Position: V147-A549). Human Cdc6 shares 87.3% amino acid (aa) sequence identity with mouse Cdc6.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.