Cdc7 rabbit polyclonal, anti-human, mouse, rat

Backgroud: This gene encodes a cell division cycle protein with kinase activity that is critical for the G1/S transition. The yeast homolog is also essential for initiation of DNA replication as cell division occurs. Overexpression of this gene product may be associated with neoplastic transformation for some tumors. Multiple alternatively spliced transcript variants that encode the same protein have been detected. [provided by RefSeq, Aug 2008],alternative products:A number of isoforms may be produced,catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,function:Seems to phosphorylate critical substrates that regulate the G1/S phase transition and/or DNA replication. Can phosphorylates MCM2 and MCM3.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC7 subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Forms a complex with either DBF4/DBF4A or DBF4B, leading to the activation of the kinase activity.,

Synonyms: CDC7, CDC7L1, Cell division cycle 7-related protein kinase, CDC7-related kinase, HsCdc7, huCdc7

Gene Name: CDC7

Gene ID: 8317

SwissProt ID: O00311

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.