CDCA4 Polyclonal Antibody

Background:
This gene encodes a protein that belongs to the E2F family of transcription factors. This protein regulates E2F-dependent transcriptional activation and cell proliferation, mainly through the E2F/retinoblastoma protein pathway. It also functions in the regulaton of JUN oncogene expression. This protein shows distinctive nuclear-mitotic apparatus distribution, it is involved in spindle organization from prometaphase, and may also play a role as a midzone factor involved in chromosome segregation or cytokinesis. Two alternatively spliced transcript variants encoding the same protein have been noted for this gene. Two pseudogenes have also been identified on chromosome 1.

Research Area: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Stem Cells

Synonyms:
CDCA 4, Cdca4, CDCA4, Cell division cycle associated 4, Cell division cycle-associated protein 4, FLJ20764, FLJ52878, Hematopoietic progenitor protein, Hepp, MGC19517, SEI 3, SEI-3/HEPP, SEI3

Immunogen: Full length fusion protein

Swissprot: Q9BXL8
Gene Accession: BC011736

Calculated MW: 26 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.2 mg/mL
Dilution: WB 1:1000-1:5000, IHC 1:50-1:300, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.