CDCP1 (clone ), anti-human, mouse, rat

Background:
CDCP1 (CUB-domain-containing protein 1) contains three extracellular CUB domains, a transmembrane domain, and two putative cytoplasmic tyrosine phosphorylation sites. Phosphorylation of the gp140 and p80 proteins is mediated by Src family kinases at various tyrosine residues, including Tyr 734. PTP family members mediate the desphosphorylation of CDCP1. The conversion of gp140 to p80 prolongs the phosphorylation state, which may affect signaling in epithelial wounds. CDCP1 acts as a marker for hematopoetic cells and also exhibits high expression in metastatic colon and breast tumors.

Alternative Name:
SIMA135, CD318, CDCP1, TRASK, 9030022E12Rik, AA409659, CD 318, CD_antigen=CD318, CD318, CD318 antigen, CDCP 1, Cdcp1, CDCP1, CUB domain containing protein 1, CUB domain-containing protein 1, E030027H19Rik, FLJ13772, FLJ22375, FLJ22969, Membrane glycoprotein gp140, MGC31813, OTTHUMP00000164120, OTTHUMP00000209568, RGD1305578, SIMA 135, SIMA135, Subtractive immunization M plus HEp3 associated 135 kDa protein, Subtractive immunization M plus HEp3-associated 135 kDa protein, Transmembrane and associated with src kinases, TRASK,

Application Dilution:
WB:1:500
ICC:1:50
IHC:1:50-1:100

Specificity: CDCP1 monoclonal antibody detects endogenous levels of CDCP1 protein.

Immunogen:
Recombinant protein.

MW: 92/72/37 kDa

Swiss-Prot: Q9H5V8(Human) Q5U462(Mouse)

Purification & Purity:
Protein affinity purified.

Format:
Mouse IgG1, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.