CDH1 monoclonal, anti-human, mouse
€0.00
In stock
SKU
AC-AM2190b
Catalog Number: AC-AM2190b
Size: 80 µl, 400 µl
Isotype: mouse IgG1,k
Clone Name: 813CT11.1.3
Applications: WB, IHC-P
Datasheet
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Size: 80 µl, 400 µl
Isotype: mouse IgG1,k
Clone Name: 813CT11.1.3
Applications: WB, IHC-P
Datasheet
Request Information
Background:
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production.
Other Names:
Cadherin-1, CAM 120/80, Epithelial cadherin, E-cadherin, Uvomorulin, CD324, E-Cad/CTF1, E-Cad/CTF2, E-Cad/CTF3, CDH1, CDHE, UVO
Target/Specificity:
Purified His-tagged CDH1 protein was used to produced this monoclonal antibody.
Antigen Type: Recombinant Protein
Gene Name: CDH1 (HGNC:1748)
Gene ID: 999
Primary Accession: P12830
NCBI Accession: NP_004351.1
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production.
Other Names:
Cadherin-1, CAM 120/80, Epithelial cadherin, E-cadherin, Uvomorulin, CD324, E-Cad/CTF1, E-Cad/CTF2, E-Cad/CTF3, CDH1, CDHE, UVO
Target/Specificity:
Purified His-tagged CDH1 protein was used to produced this monoclonal antibody.
Antigen Type: Recombinant Protein
Gene Name: CDH1 (HGNC:1748)
Gene ID: 999
Primary Accession: P12830
NCBI Accession: NP_004351.1
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
| Is Featured? | No |
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