CDH11 antibody (clone 4D10), anti-human
€435.00
In stock
SKU
AC-AT1471a
Catalog Number: AC-AT1471a
Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: WB, E
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Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: WB, E
Request Information AC-AT1471a">Request Information
Background:
This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance.
Other Names:
Cadherin-11, OSF-4, Osteoblast cadherin, OB-cadherin, CDH11
Antigen Type:
Recombinant Protein
Gene Name: CDH11
Gene ID: 1009
NCBI Accession: NP_001788.2
Primary Accession: P55287
Other Accession: NM_001797
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance.
Other Names:
Cadherin-11, OSF-4, Osteoblast cadherin, OB-cadherin, CDH11
Antigen Type:
Recombinant Protein
Gene Name: CDH11
Gene ID: 1009
NCBI Accession: NP_001788.2
Primary Accession: P55287
Other Accession: NM_001797
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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