CDH12 polyclonal (N-term), anti-human
€0.00
In stock
SKU
AC-AP1473a
Catalog Number: AC-AP1473a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB13742
Applications: WB, IHC-P
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB13742
Applications: WB, IHC-P
Datasheet
Request Information
Background:
CDH12 is a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development, perhaps specifically during synaptogenesis.
Other Names:
Cadherin-12, Brain cadherin, BR-cadherin, Neural type cadherin 2, N-cadherin 2, CDH12
Target/Specificity:
This CDH12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 62-90 amino acids from the N-terminal region of human CDH12.
Antigen Region:
62-90
Antigen Type: Synthetic Peptide
Gene Name: CDH12
Gene ID: 1010
Primary Accession: P55289
NCBI Accession: NP_004052.2
Other Accession: Q5RJH3
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
CDH12 is a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development, perhaps specifically during synaptogenesis.
Other Names:
Cadherin-12, Brain cadherin, BR-cadherin, Neural type cadherin 2, N-cadherin 2, CDH12
Target/Specificity:
This CDH12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 62-90 amino acids from the N-terminal region of human CDH12.
Antigen Region:
62-90
Antigen Type: Synthetic Peptide
Gene Name: CDH12
Gene ID: 1010
Primary Accession: P55289
NCBI Accession: NP_004052.2
Other Accession: Q5RJH3
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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