CDH16 Antibody (C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP13746b
Background:
This gene is a member of the cadherin superfamily, genesencoding calcium-dependent, membrane-associated glycoproteins.Mapped to a previously identified cluster of cadherin genes onchromosome 16q22.1, the gene localizes with superfamily membersCDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of anextracellular domain containing 6 cadherin domains, a transmembraneregion and a truncated cytoplasmic domain but lacks the prosequenceand tripeptide HAV adhesion recognition sequence typical of mostclassical cadherins. Expression is exclusively in kidney, where theprotein functions as the principal mediator of homotypic cellularrecognition, playing a role in the morphogenic direction of tissuedevelopment.
Other Names:
Cadherin-16, Kidney-specific cadherin, Ksp-cadherin, CDH16
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13746b was selected from the C-term region of CDH16. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: CDH16
Gene ID: 1014
Primary Accession: O75309
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene is a member of the cadherin superfamily, genesencoding calcium-dependent, membrane-associated glycoproteins.Mapped to a previously identified cluster of cadherin genes onchromosome 16q22.1, the gene localizes with superfamily membersCDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of anextracellular domain containing 6 cadherin domains, a transmembraneregion and a truncated cytoplasmic domain but lacks the prosequenceand tripeptide HAV adhesion recognition sequence typical of mostclassical cadherins. Expression is exclusively in kidney, where theprotein functions as the principal mediator of homotypic cellularrecognition, playing a role in the morphogenic direction of tissuedevelopment.
Other Names:
Cadherin-16, Kidney-specific cadherin, Ksp-cadherin, CDH16
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13746b was selected from the C-term region of CDH16. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: CDH16
Gene ID: 1014
Primary Accession: O75309
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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