CDH16 (clone 6H6E2), anti-human
€0.00
In stock
SKU
BT-MCA3873
Catalog Number: BT-MCA3873
Size(s): 50μL, 100μL
Isotype: Mouse IgG1
Reactivity: human
Application(s): WB, IHC, ICC, FCM
Datasheet
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Size(s): 50μL, 100μL
Isotype: Mouse IgG1
Reactivity: human
Application(s): WB, IHC, ICC, FCM
Datasheet
Request Information
Background:
This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. Alternatively spliced transcript variants encoding distinct isoforms have been identified.
Research Area: Signal Transduction
Synonyms: KSP-Cadherin
Immunogen: Purified recombinant fragment of human CDH16 (AA: EX(558-721)) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide.
Storage:
4°C|-20°C for long term storage
This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. Alternatively spliced transcript variants encoding distinct isoforms have been identified.
Research Area: Signal Transduction
Synonyms: KSP-Cadherin
Immunogen: Purified recombinant fragment of human CDH16 (AA: EX(558-721)) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide.
Storage:
4°C|-20°C for long term storage
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