CDH16 polyclonal (C-term), anti-human

CDH16 polyclonal (C-term), anti-human

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In stock
SKU
AC-AP13746b
Catalog Number: AC-AP13746b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB33734
Applications: WB
Datasheet

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Background:
This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development.

Other Names:
Cadherin-16, Kidney-specific cadherin, Ksp-cadherin, CDH16

Target/Specificity:
This CDH16 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 796-824 amino acids from the C-terminal region of human CDH16.

Antigen Region:
796-824

Antigen Type: Synthetic Peptide

Gene Name: CDH16
Gene ID: 1014
Primary Accession: O75309
NCBI Accession: NP_001191673.1;NP_001191674.1;NP_001191675.1;NP_004053.1
Other Accession: NP_004053.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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