CDH17 (clone 7D10E1), anti-human

Background:
This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants.

Research Area: Signal Transduction

Synonyms: HPT1, CDH16, HPT-1

Immunogen: Purified recombinant fragment of human CDH17 (AA: extra(600-707)) expressed in E. Coli.

Formulation: Purified antibody in PBS with 0.05% sodium azide.

Storage:
4°C|-20°C for long term storage