CDH23 polyclonal, anti-human, mouse, rat

Background:
This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Upregulation of this gene may also be associated with breast cancer. Alternative splice variants encoding different isoforms have been described.

Synonyms: CDHR23, USH1D

Cellular Location: Cell membrane Single-pass type I membrane protein

Immunogen:
Recombinant protein of human CDH23

Gene Symbol: CDH23

Gene ID: 64072

Swiss prot: Q9H251

Calculated MW: 369kDa

Recommended dilution:
WB 1:500-2000, IHC 1:100-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.