CDH3 polyclonal, anti-human, mouse

Background:
This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy.

Synonyms: CDHP, HJMD, PCAD

Cellular Location: Membrane Cytoplasm

Immunogen:
Recombinant protein of human CDH3

Gene Symbol: CDH3

Gene ID: 1001

Swiss prot: P22223

Calculated MW: 91kDa

Recommended dilution:
WB 1:200-1000, IHC 1:5-20,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.