CDH4 polyclonal (N-term), anti-human
€0.00
In stock
SKU
AC-AP1401A
Catalog Number: AC-AP1401A
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB13654
Applications: IHC-P, IF, FC, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB13654
Applications: IHC-P, IF, FC, WB
Datasheet
Request Information
Background:
CDH4 is a classical cadherin from the cadherin superfamily. It is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization.
Other Names:
Cadherin-4, Retinal cadherin, R-CAD, R-cadherin, CDH4
Target/Specificity:
This CDH4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 175-203 amino acids from the N-terminal region of human CDH4.
Antigen Region:
175-203
Antigen Type: Synthetic Peptide
Gene Name: CDH4
Gene ID: 1002
Primary Accession: P55283
NCBI Accession: NP_001239267.1;NP_001239268.1;NP_001785.2
Other Accession: Q63149; P39038
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
CDH4 is a classical cadherin from the cadherin superfamily. It is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization.
Other Names:
Cadherin-4, Retinal cadherin, R-CAD, R-cadherin, CDH4
Target/Specificity:
This CDH4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 175-203 amino acids from the N-terminal region of human CDH4.
Antigen Region:
175-203
Antigen Type: Synthetic Peptide
Gene Name: CDH4
Gene ID: 1002
Primary Accession: P55283
NCBI Accession: NP_001239267.1;NP_001239268.1;NP_001785.2
Other Accession: Q63149; P39038
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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