CDK11A/CDK11B polyclonal, anti-human, mouse

Background:
Cyclin-dependent kinases (CDKs) are a family of protein kinases first discovered for their role in regulating the cell cycle. They are also involved in regulating transcription, mRNA processing, and the differentiation of nerve cells. They are present in all known eukaryotes, and their regulatory function in the cell cycle has been evolutionarily conserved. CDKs are relatively small proteins, with molecular weights ranging from 34 to 40 kDa, and contain little more than the kinase domain. By definition, a CDK binds a regulatory protein called a cyclin. Without cyclin, CDK has little kinase activity; only the cyclin-CDK complex is an active kinase. CDKs phosphorylate their substrates on serines and threonines, so they are serine-threonine kinases.

Synonyms: CDC2L2, CDC2L3, p58GTA, PITSLRE, CDK11-p46, CDK11-p58, CDK11-p110 / p58, PK58, CDK11, CLK-1, CDC2L1, p58CLK-1, CDK11-p46, CDK11-p58, p58CDC2L1, CDK11-p110

Cellular Location: Cytoplasm

Immunogen:
A synthetic peptide of human CDK11A/CDK11B

Gene Symbol: CDK11A/CDK11B

Gene ID: 728642/984

Swiss prot: Q9UQ88/P21127

Calculated MW: 93kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.