Cdk2 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
CDK2, Cyclin-Dependent Kinase2, is also know as P33. The CDK2 protein was highly homologous to p34(CDC2) kinase and more significantly homologous to Xenopus Eg1 kinase, suggesting that CDK2 is the human homolog of Eg1. The CDK2 gene is mapped to 12q13, the same region to which the CDK4 gene maps. Human cyclin A binds independently to 2 kinases, p34(cdc2) or p33. In adenovirus-transformed cells, the viral E1A oncoprotein seems to associate with p33/cyclin A but not with p34(cdc2)/cyclin A. The gene for p33 shares 65% sequence identity with p34(cdc2). P33(cdk2) plays a unique role in cell cycle regulation of vertebrate cells.

Description:
Rabbit IgG polyclonal antibody for Cyclin-dependent kinase 2 (CDK2) detection. Tested with WB in Human, Mouse, Rat.

Synonyms:
Cdc2 related protein kinase antibody, cdc2-related protein kinase antibody, Cdk 2 antibody, CDK2 antibody, CDK2_HUMAN antibody, Cell devision kinase 2 antibody, Cell division kinase 2 antibody, Cell division protein kinase 2 antibody, Cyclin dependent kinase 2 antibody, cyclin dependent kinase 2-alpha antibody, Cyclin-dependent kinase 2 antibody, p33 protein kinase antibody, p33(CDK2) antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human Cdk2(277-298aa AKAALAHPFFQDVTKPVPHLRL), identical to the related rat and mouse sequences.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human.
Predicted to work with: mouse, rat.

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.