Cdk4 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Cyclin-dependent kinase-4(CDK4) is a protein-serine kinase involved in the cell cycle. Human cell division is regulated primarily at the G1-to-S or the G2-to-M boundaries within the cell cycle. The complexes formed by CDK4 and the D-type cyclins are involved in the control of cell proliferation during the G1 phase. CDK4 is inhibited by p16, also known as cyclin-dependent kinase inhibitor-2. CDK4 is mapped to 12q14. CDK4 expression and activity are required for cytokine responsiveness in T cells.

Description:
Rabbit IgG polyclonal antibody for Cyclin-dependent kinase 4 (CDK4) detection. Tested with WB in Human, Mouse, Rat.

Synonyms:
Cdk 4 antibody, cdk4 antibody, CDK4 protein antibody, CDK4_HUMAN antibody, Cell division kinase 4 antibody, Cell division protein kinase 4 antibody, CMM 3 antibody, CMM3 antibody, Crk3 antibody, Cyclin dependent kinase 4 antibody, Cyclin-dependent kinase 4 antibody, Melanoma cutaneous malignant 3 antibody, MGC14458 antibody, p34 cdk4 antibody, PSK J3 antibody, PSK-J3 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of mouse Cdk4(283-303aa RISAFRALQHSYLHKEESDAE), different from the related rat sequence by one amino acid, and from the related human sequence by four amino acids.A synthetic peptide corresponding to a sequence at the C-terminus of mouse Cdk4(283-303aa RISAFRALQHSYLHKEESDAE), different from the related rat sequence by one amino acid, and from the related human sequence by four amino acids.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat .
Predicted to work with: mouse.

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.