CDK5 Polyclonal Antibody

Background:
Cyclin-dependent kinases (CDKs) are serine/threonine kinases that are activated by cyclins and govern eukaryotic cell cycle progression. While CDK5 shares high sequence homology with its family members, it is thought mainly to function in postmitotic neurons to regulate the cytoarchitecture of these cells. Analogous to cyclins, the regulatory subunits p35 and p39 associate with and activate CDK5 despite the lack of sequence homology.

Research Area: Cancer, Cell Biology, Metabolism, Neuroscience

Synonyms:
Cdk 5, Cdk5, CDK5, Cell division protein kinase 5, Crk6, Cyclin dependent kinase 5, Cyclin-dependent kinase 5, Protein kinase CDK5 splicing, PSSALRE, Serine threonine protein kinase PSSALRE, Serine/threonine-protein kinase PSSALRE, Tau protein kinase II catalytic subunit, TPKII catalytic subunit

Immunogen: Recombinant protein of human CDK5

Swissprot: Q00535
Gene Accession: BC005115

Calculated MW: 33 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.3 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:25-1:100

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-32497/sc-173/sc-750