CDK7 Polyclonal Antibody

Background:
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle.

Research Area: Cancer, Cell Biology, Epigenetics and Nuclear Signaling

Synonyms:
39 kDa protein kinase, CAK, CAK1, Cdk activating kinase, CDK-activating kinase 1, CDK-activating kinase, cdk7, CDK7, CDKN7, Cell division protein kinase 7, Cyclin dependent kinase 7, cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase), Cyclin-dependent kinase 7, HCAK, Homolog of Xenopus MO15 Cdk activating kinase, Kinase subunit of CAK, MO15, MO15, Xenopus, homolog of, P39 Mo15, p39MO15, Serine threonine kinase Stk1, Serine/threonine protein kinase 1, Serine/threonine protein kinase MO15, STK1, TFIIH basal transcription factor complex kinase subunit

Immunogen: Recombinant protein of human CDK7

Swissprot: P50613
Gene Accession: BC000834

Calculated MW: 39 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.3 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:15-1:50

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-856/sc-723/sc-529