CDK7 Polyclonal Antibody

Background:
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle.

Research Area: Cancer, Cell Biology, Epigenetics and Nuclear Signaling

Synonyms:
CDK7, CAK, CAK1, CDKN7, HCAK, MO15, STK1, p39MO15

Immunogen: Recombinant fusion protein of human CDK7 (NP_001790.1).

Swissprot: P50613
Gene ID: 1022

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "IHC 1:50-1:200 IF 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.