Cdk9 polyclonal, anti-human, rat

Quantity: 100 µg

Background:
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS.

Description:
Rabbit IgG polyclonal antibody for Cyclin-dependent kinase 9 (CDK9) detection. Tested with WB, IHC-P in Human, Rat.

Synonyms:
C 2k antibody, C-2K antibody, CDC2 related kinase antibody, CDC2L4 antibody, Cdk 9 antibody, Cdk9 antibody, CDK9_HUMAN antibody, Cell division cycle 2 like protein kinase 4 antibody, Cell division cycle 2-like protein kinase 4 antibody, Cell division protein kinase 9 antibody, CTK1 antibody, Cyclin dependent kinase 9 antibody, Cyclin-dependent kinase 9 antibody, PITALRE antibody, Serine threonine protein kinase PITALRE antibody, Serine/threonine-protein kinase PITALRE antibody, TAK antibody, Tat associated kinase complex catalytic subunit antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human Cdk9 recombinant protein (Position: H141-F372). Human Cdk9 shares 99.1% amino acid (aa) sequence identity with both mouse and rat Cdk9.E.coli-derived human Cdk9 recombinant protein (Position: H141-F372). Human Cdk9 shares 99.1% amino acid (aa) sequence identity with both mouse and rat Cdk9.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.