CDK9 Polyclonal Antibody

Background:
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS.

Research Area: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Immunology, Microbiology

Synonyms:
CDK9, C-2k, CDC2L4, CTK1, PITALRE, TAK

Immunogen: Recombinant fusion protein of human CDK9 (NP_001252.1).

Swissprot: P50750
Gene ID: 1025

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.