CDKN1B antibody (clone 4B4-E6), anti-human

Background:
This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state.

Other Names:
Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinase inhibitor p27, p27Kip1, CDKN1B, KIP1

Antigen Type:
Recombinant Protein

Gene Name: CDKN1B {ECO:0000303|PubMed:20824794}
Gene ID: 1027
NCBI Accession: NP_004055.1
Primary Accession: P46527
Other Accession: BC001971
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .