CDKN1B C-terminal region polyclonal, anti-human

Background:
Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1- CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry.

Other Names:
Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinase inhibitor p27, p27Kip1, CDKN1B, KIP1

Immunogen:
The immunogen for anti-CDKN1B antibody: synthetic peptide directed towards the C terminal of human CDKN1B

Gene Name:
CDKN1B {ECO:0000303|PubMed:20824794}
Gene Name:
1027
NCBI Accession:
NP_004055
Primary Accession: P46527
Other Accession: NM_004064;NP_004055
Purification: Affinity Purified
Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.