CDKN1B polyclonal, anti-human, mouse, rat

Background:
Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. Acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry.

Synonyms: CDKN4, KIP1, MEN1B, MEN4, P27KIP1

Cellular Location: Cytoplasm

Immunogen:
A synthetic peptide of human CDKN1B

Gene Symbol: CDKN1B

Gene ID: 1027

Swiss prot: P46527

Calculated MW: 22kDa

Recommended dilution:
WB 1:3000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.